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| Product Name | HER2, Active, Recombinant, Human |
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| Description | Purity ≥ 90% (SDS-PAGE). HER2 gene encodes a cell-surface glycoprotein tyrosine kinase receptor with extensive homology to the epidermal growth factor receptor. HER2 is an oncogene and overexpression of unaltered HER2 coding sequences in NIH 3T3 cells results in cellular transformation and tumorigenesis (1). HER2 is amplified in about 30% of primary human breast malignancies and overexpression of HER2 is associated with the most aggressive tumors that show uncontrolled proliferation, resistance to apoptosis and increased motility (2). Description: Recombinant human HER2 (aa 676-end), containing a GST tag at the N-terminus, and expressed in Baculovirus (Sf9 insect cells). Accession Number: NM_004448 Molecular Weight: ~116kD Specific Activity: ~10nmol/min/mg as per activity assay protocol. |
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| Size | 5ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | HER2, Active, Recombinant, Human (ERBB2, Receptor tyrosine-protein kinase erbB-2, Tyrosine Kinase-type Cell Surface Receptor Her2, neu Oncoprotein, CD340, Proto-oncogene c-ErbB-2, Proto-oncogene Neu, Metastatic lymph node gene 19 protein, p185erbB2) |
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| Gene, Accession, CAS # | HER2, Gene ID: 2064, Accession: NM_004448, SwissProt: P04626 |
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| Catalog # | 219840 |
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| Order / More Info | HER2, Active, Recombinant, Human from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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