| 产品详情 |
| Edit |   |
|---|
| Product Name | GREM1, Recombinant, Human, aa25-184, His-Tag |
|---|
| Description | Purity ~90% (SDS-PAGE). GREM1 is a member of the BMP (bone morphogenic protein) antagonist family. Like BMPs, BMP antagonists contain cystine knots and typically form homo- and heterodimers. The CAN (cerberus and dan) subfamily of BMP antagonists, to which this protein belongs, is characterized by a C-terminal cystine knot with an eight-membered ring. The antagonistic effect of the secreted glycosylated protein is likely due to its direct binding to BMP proteins. As an antagonist of BMP, this protein may play a role in regulating organogenesis, body patterning, and tissue differentiation. In mouse, this protein has been shown to relay the sonic hedgehog (SHH) signal from the polarizing region to the apical ectodermal ridge during limb bud outgrowth. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. Source: Recombinant protein corresponding to aa25-184 from human GREM1 at N-terminal, fused to His-tag expressed in E.coli. Molecular Weigh |
|---|
| Size | 100ug |
|---|
| Concentration | n/a |
|---|
| Applications | n/a |
|---|
| Other Names | GREM1, Recombinant, Human, aa25-184, His-Tag (Gremlin-1 Isoform 1, CKTSF1B1, DAND2, DRM, GREMLIN, IHG-2, PIG2) |
|---|
| Gene, Accession, CAS # | n/a |
|---|
| Catalog # | 138659 |
|---|
| Price | |
|---|
| Order / More Info | GREM1, Recombinant, Human, aa25-184, His-Tag from UNITED STATES BIOLOGICAL |
|---|
| Product Specific References | n/a |
|---|
| 产品资料 |
|
|