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| Product Name | Cathepsin D, Recombinant, Human |
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| Description | Cathepsin D is a lysosomal aspartic protease of the pepsin family. Human Cathepsin D is synthesized as a precursor protein, consisting of a signal peptide (residues 1-18), a propeptide (residues 19-64), and a mature chain (residues 65-412). The mature chain can be processed further to the light (residues 65-161) and heavy (residues 169-412) chains. It is an estrogen-regulated lysosomal protease that has been suggested to facilitate cancer cell migration and invasion by digesting the basement membrane, extracellular matrix, and xonnective tissue. Because of its mitogenic and proteolytic activities, it has been implicated as a prognostic marker in many tumor types. It could also play a role in Alzheimer's Disease. Source: Recombinant protein corresponding to full length human Cathepsin D, expressed in E. coli. Molecular Weight: ~48kD (SDS-PAGE) AA Sequence: mqpssllpla lcllaapasa lvriplhkft sirrtmsevg gsvedliakg pvskysqavp avtegpipev lknymdaqyy geigigtppq cftvvfdtgs snlwvpsihc klldiacwih |
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| Size | 2ug, 10ug |
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| Concentration | n/a |
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| Applications | ELISA WB |
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| Other Names | n/a |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | 299330 |
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| Order / More Info | Cathepsin D, Recombinant, Human from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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