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| Product Name | Recombinant Human X-ray repair cross-complementing protein 5 |
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| Description | 251-455aa; Partial. MW: 27.53kD. Purity >90% as determined by SDS-PAGE. Single-stranded DNA-dependent ATP-dependent helicase. Has a role in chromosome translocation. The DNA helicase II complex binds preferentially to fork-like ends of double-stranded DNA in a cell cycle-dependent manner. It works in the 3'-5' direction. Binding to DNA may be mediated by XRCC6. Involved in DNA non-homologous end joining (NHEJ) required for double-strand break repair and V(D)J recombination. The XRCC5/6 dimer act |
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| Size | 0.01 mg (E-Coli), 0.05 mg (E-Coli), 0.1 mg (E-Coli), 0.2 mg (E-Coli), 0.5 mg (E-Coli) |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | [86 kDa subunit of Ku antigen; ATP-dependent DNA helicase 2 subunit 2; ATP-dependent DNA helicase II 80 kDa subunit; CTC box-binding factor 85 kDa subunit; CTC85; CTCBF; DNA repair protein XRCC5; Ku80; Ku86; Lupus Ku autoantigen protein p86; Nuclear factor IV; Thyroid-lupus autoantigen; TLAA; X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining)] |
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| Gene, Accession, CAS # | XRCC5, Gene ID: 7520, Accession: NP_066964.1 |
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| Catalog # | MBS956673 |
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| Order / More Info | Recombinant Human X-ray repair cross-complementing protein 5 from MYBIOSOURCE INC. |
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| Product Specific References | cDNA-derived amino acid sequence of the 86-kDa subunit of the Ku antigen.Yaneva M., Wen J., Ayala A., Cook R.J. Biol. Chem. 264:13407-13411(1989) Isolation and characterization of cDNA encoding the 80-kDa subunit protein of the human autoantigen Ku (p70/p80) recognized by autoantibodies from patients with scleroderma-polymyositis overlap syndrome.Mimori T., Ohosone Y., Hama N., Suwa A., Akizuki M., Homma M., Griffith A.J., Hardin J.A.Proc. Natl. Acad. Sci. U.S.A. 87:1777-1781(1990) Complete sequ |
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