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| Product Name | Recombinant Human X-ray repair cross-complementing protein 6 |
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| Description | 6-222aa; Partial. MW: 28.9kD. Purity >90% as determined by SDS-PAGE. Single-stranded DNA-dependent ATP-dependent helicase. Has a role in chromosome translocation. The DNA helicase II complex binds preferentially to fork-like ends of double-stranded DNA in a cell cycle-dependent manner. It works in the 3'-5' direction. Binding to DNA may be mediated by XRCC6. Involved in DNA non-homologous end joining (NHEJ) required for double-strand break repair and V(D)J recombination. The XRCC5/6 dimer acts a |
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| Size | 0.01 mg, 0.05 mg, 0.1 mg, 0.2 mg, 0.5 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | [5'-deoxyribose-5-phosphate lyase Ku70; 5'-dRP lyase Ku70; 70 kDa subunit of Ku antigen; ATP-dependent DNA helicase 2 subunit 1; ATP-dependent DNA helicase II 70 kDa subunit; CTC box-binding factor 75 kDa subunit; CTC75; CTCBF; DNA repair protein XRCC6; Lupus Ku autoantigen protein p70; Ku70; Thyroid-lupus autoantigen; TLAA; X-ray repair complementing defective repair in Chinese hamster cells 6] |
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| Gene, Accession, CAS # | XRCC6/G22P1, Gene ID: 2547, Accession: NP_001275905.1 |
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| Catalog # | MBS1265152 |
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| Order / More Info | Recombinant Human X-ray repair cross-complementing protein 6 from MYBIOSOURCE INC. |
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| Product Specific References | Cloning and characterization of a cDNA that encodes a 70-kDa novel human thyroid autoantigen.Chan J.Y., Lerman M.I., Prabhakar B.S., Isozaki O., Santisteban P., Kuppers R.C., Oates E.L., Notkins A.L., Kohn L.D.J. Biol. Chem. 264:3651-3654(1989) |
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