| 产品详情 |
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| Product Name | NCKX3, Control Peptide |
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| Description | Control peptide for N0559-06 and N0559-06A. Ca2+ plays a critical role in intracellular signaling. Intracellular Ca2+ levels are tightly controlled by continuos removal of Ca2+ via ATP-driven Ca2+ pump in the endoplasmic reticulum and plasma membrane, and the Na+/Ca2+ exchangers (NCX), in the plasma membrane. NCX can move Ca2+ either into or out of cells, depending on the net Na+, Ca2+, and K+ gradient across the membrane. In most cells, 3 Na+ are exchanged for 1 Ca2+. Several genes code for the 3 NCX (NCX1, NCX2, and NCX3), and three in the NCKX family (NCKX1, NCKX2, NCKX3). NCX share significant sequence homology (~70%), display 11 TM domains, a large central, intracellular hydrophilic regulatory loop between TM5 and 6, extracellular N-terminus and cytoplasmic C-terminus. The N-terminal signal peptide is cleaved off from the mature exchanger protein. In vertebrate photoreceptors, some neurons, and certain other cells, 3 K+ are transported in the same direction as Ca2+, with coupling |
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| Size | 100ug |
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| Concentration | n/a |
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| Applications | ELISA |
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| Other Names | NCKX3, Control Peptide (Sodium/Potassium/Calcium Exchanger 3, a(+)/K(+)/Ca(2+)-exchange Protein 3, Solute Carrier Family 24 Member 3, SLC24A3) |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | N0559-06B |
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| Price | |
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| Order / More Info | NCKX3, Control Peptide from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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