| 产品详情 |
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| Product Name | c-Jun AP-1, Control Peptide (v-Jun) |
| Description | c-Jun is a component of the transcription factor AP-1, which binds and activates transcription at TRE/AP-1 elements. The transcriptional activity of c- Jun is regulated by phosphorylation at Ser63 and Ser73 (1,2). Extracellular signals, including growth factors, transforming oncoproteins and UV irradiation, stimulate phosphorylation of c-Jun at Ser63/73 and activate c-Jun-dependent transcription. Mutation of Ser63/73 renders c-Jun nonresponsive to mitogenic and stressinduced signaling pathways. The MAP kinase homologue SAPK/JNK binds to the N-terminal region of c-Jun and phosphorylates c-Jun at Ser63/73. In addition, the activity of SAPK/JNK is stimulated by the same signals that activate c-Jun (3,4). Applications: Suitable for use in ELISA or for antigen applications in immunological protocols. |
| Size | 1mg, 5x1mg |
| Concentration | n/a |
| Applications | n/a |
| Other Names | n/a |
| Gene, Accession, CAS # | n/a |
| Catalog # | C5815-12A |
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| Order / More Info | c-Jun AP-1, Control Peptide (v-Jun) from UNITED STATES BIOLOGICAL |
| Product Specific References | n/a |
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