产品名称 c-Jun AP-1, Control Peptide (v-Jun) from UNITED STATES BIOLOGICAL
产品货号 C5815-12A
产品价格 现货询价,电话:010-67529703
产品规格 1mg, 5x1mg
产品品牌 UNITED STATES BIOLOGICAL
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Product Namec-Jun AP-1, Control Peptide (v-Jun)
Descriptionc-Jun is a component of the transcription factor AP-1, which binds and activates transcription at TRE/AP-1 elements. The transcriptional activity of c- Jun is regulated by phosphorylation at Ser63 and Ser73 (1,2). Extracellular signals, including growth factors, transforming oncoproteins and UV irradiation, stimulate phosphorylation of c-Jun at Ser63/73 and activate c-Jun-dependent transcription. Mutation of Ser63/73 renders c-Jun nonresponsive to mitogenic and stressinduced signaling pathways. The MAP kinase homologue SAPK/JNK binds to the N-terminal region of c-Jun and phosphorylates c-Jun at Ser63/73. In addition, the activity of SAPK/JNK is stimulated by the same signals that activate c-Jun (3,4). Applications: Suitable for use in ELISA or for antigen applications in immunological protocols.
Size1mg, 5x1mg
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Catalog #C5815-12A
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