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| Product Name | TXNRD1, Recombinant, Human, 508aa, His-Tag |
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| Description | Purity ~95% (SDS-PAGE). Thioredoxin reductase 1, cytoplasmic is an enzyme that in humans is encoded by the TXNRD1 gene. This gene encodes a member of the family of pyridine nucleotide oxidoreductases. This protein reduces thioredoxins as well as other substrates, and plays a role in selenium metabolism and protection against oxidative stress. The functional enzyme is thought to be a homodimer which uses FAD as a cofactor. Inhibition of TXNRD1 activity may provide for potential treatments of cancer, AIDS and other autoimmune diseases as well as bacterial infections and parasitic diseases. Recombinant protein corresponding to 508aa from human TXNRD1, fused to His-tag at N-terminal, expressed in E. coli. Molecular Weight: ~55.7kD (508aa + NT His Tag) Biological Activity: Specific activity is 0.48-0.60units/ml and was measured in a coupled assay with DTNB and NADPH. The amount of TNB generated by NADPH was measured in absorbance at 412nm. Amino Acid Sequence: MGSSHHHHHH SSGLVPRGSH MYDYDLII |
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| Size | 100ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | TXNRD1, Recombinant, Human, 508aa, His-Tag (Thioredoxin Reductase 1, GRIM-12, MGC9145, TR, TR1, TRXR1, TXNR) |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | 170092 |
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| Order / More Info | TXNRD1, Recombinant, Human, 508aa, His-Tag from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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