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| Product Name | Recombinant Human Tumor necrosis factor alpha-induced protein 8 |
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| Description | 2-198aa; Full Length. MW: 50.3kD. Purity >90% as determined by SDS-PAGE. Acts as a negative mediator of apoptosis and may play a role in tumor progression. Suppresses the TNF-mediated apoptosis by inhibiting caspase-8 activity but not the processing of procaspase-8, subsequently resulting in inhibition of BID cleavage and caspase-3 activation. |
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| Size | 0.01 mg, 0.05 mg, 0.1 mg, 0.2 mg, 0.5 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | [Head and neck tumor and metastasis-related protein; MDC-3.13; NF-kappa-B-inducible DED-containing protein; NDEDSCC-S2TNF-induced protein GG2-1] |
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| Gene, Accession, CAS # | TNFAIP8, Gene ID: 25816, Accession: NP_001071122.1 |
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| Catalog # | MBS956964 |
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| Order / More Info | Recombinant Human Tumor necrosis factor alpha-induced protein 8 from MYBIOSOURCE INC. |
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| Product Specific References | Vascular endothelial genes that are responsive to tumor necrosis factor-alpha in vitro are expressed in atherosclerotic lesions, including inhibitor of apoptosis protein-1, stannin, and two novel genes.Horrevoets A.J.G., Fontijn R.D., van Zonneveld A.J., de Vries C.J.M., ten Cate J.W., Pannekoek H.Blood 93:3418-3431(1999) |
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