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| Product Name | Recombinant Human Tumor Necrosis Factor-alpha Variant (rHu TNF-alpha Variant) |
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| Description | Purity >95% by SDS-PAGE and HPLC analyses. The clinical use of the potent antitumor activity of TNF-alphahas been limited by the proinflammatory side effects including fever, dose-limiting hypotension, hepatotoxicity, intravascular thrombosis, and hemorrhage. Designing clinically applicable TNF-alphamutants with low systemic toxicity has been an intense pharmacological interest. Human TNF-alpha, which binds to the murine TNF-R55 but not to the murine TNF-R75, exhibits retained antitumor activity |
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| Size | 0.01 mg, 0.05 mg, 1 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | [Tumor Necrosis Factor- alpha Variant; human TNF-alpha Variant; Human Tumor Necrosis Factor-alpha (variant); Tumor Necrosis Factor- alpha Variant; human TNF-a Variant; Recombinant Human Tumor Necrosis Factor-alpha Variant (rHu TNF-a Variant)] |
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| Gene, Accession, CAS # | tnfa, Gene ID: 100169660, Accession: NP_001121579.1 |
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| Catalog # | MBS546029 |
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| Order / More Info | Recombinant Human Tumor Necrosis Factor-alpha Variant (rHu TNF-alpha Variant) from MYBIOSOURCE INC. |
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| Product Specific References | n/a |
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