| 产品详情 |
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| Product Name | Recombinant Human Tumor necrosis factor ligand superfamily member 10 |
| Description | 39-281aa; Extracellular Domain. MW: 55.8kD. Purity >90% as determined by SDS-PAGE. Cytokine that binds to TNFRSF10A/TRAILR1, TNFRSF10B/TRAILR2, TNFRSF10C/TRAILR3, TNFRSF10D/TRAILR4 and possibly also to TNFRSF11B/OPG. Induces apoptosis. Its activity may be modulated by binding to the decoy receptors TNFRSF10C/TRAILR3, TNFRSF10D/TRAILR4 and TNFRSF11B/OPG that cannot induce apoptosis. |
| Size | 0.01 mg, 0.05 mg, 0.1 mg, 0.2 mg, 0.5 mg |
| Concentration | n/a |
| Applications | n/a |
| Other Names | [Apo-2 ligand; Apo-2; LTNF-related apoptosis-inducing ligand; Protein TRAIL; CD253] |
| Gene, Accession, CAS # | TNFSF10, Gene ID: 8743, Accession: NP_001177871.1 |
| Catalog # | MBS717233 |
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| Order / More Info | Recombinant Human Tumor necrosis factor ligand superfamily member 10 from MYBIOSOURCE INC. |
| Product Specific References | Identification and characterization of a new member of the TNF family that induces apoptosis.Wiley S.R., Schooley K., Smolak P.J., Din W.S., Huang C.-P., Nicholl J.K., Sutherland G.R., Davis-Smith T., Rauch C., Smith C.A., Goodwin R.G.Immunity 3:673-682(1995) Induction of apoptosis by Apo-2 ligand, a new member of the tumor necrosis factor cytokine family.Pitti R.M., Marsters S.A., Ruppert S., Donahue C.J., Moore A., Ashkenazi A.J. Biol. Chem. 271:12687-12690(1996) Isolation of a TRAIL antagonis |
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