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| Product Name | Recombinant Human Tumor necrosis factor ligand superfamily member 6 |
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| Description | 130-281aa; Extracellular Domain. MW: 21.4kD. Purity >90% as determined by SDS-PAGE. Cytokine that binds to TNFRSF6/FAS, a receptor that transduces the apoptotic signal into cells. May be involved in cytotoxic T-cell mediated apoptosis and in T-cell development. TNFRSF6/FAS-mediated apoptosis may have a role in the induction of peripheral tolerance, in the antigen-stimulated suicide of mature T-cells, or both. Binding to the decoy receptor TNFRSF6B/DcR3 modulates its effects. |
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| Size | 0.01 mg (E-Coli), 0.01 mg (Yeast), 0.05 mg (E-Coli), 0.05 mg (Yeast), 0.1 mg (E-Coli) |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | [Apoptosis antigen ligand; APTLCD95 ligand; CD95-LFas antigen ligand; Fas ligand; FasL; CD178] |
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| Gene, Accession, CAS # | FASLG, Gene ID: 356, Accession: NP_000630.1 |
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| Catalog # | MBS967590 |
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| Order / More Info | Recombinant Human Tumor necrosis factor ligand superfamily member 6 from MYBIOSOURCE INC. |
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| Product Specific References | Fas ligand mediates activation-induced cell death in human T lymphocytes.Alderson M.J. Exp. Med. 181:71-77(1995) Human Fas ligandgene structure, chromosomal location and species specificity.Takahashi T., Tanaka M., Inazawa J., Abe T., Suda T., Nagata S.Int. Immunol. 6:1567-1574(1994) Schaetzlein C.E., Poehlmann R., Philippsen P., Eibel H.Role of Fas ligand in apoptosis induced by hepatitis C virus infection.Mita E., Hayashi N., Iio S., Takehara T., Hijioka T., Kasahara A., Fusamoto H., Kamada T. |
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