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| Product Name | Recombinant Human Tumor necrosis factor ligand superfamily member 18 protein (TNFSF18) (Active) |
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| Description | 74-199aa, Partial. MW: 14.3 kDa. Purity ≥98% as determined by SDS-PAGE and HPLC. Cytokine that binds to TNFRSF18/AITR/GITR. Regulates T-cell responses. Can function as costimulator and lower the threshold for T-cell activation and T-cell proliferation. Important for interactions between activated T-lymphocytes and endothelial cells. Mediates activation of NF-kappa-B. Triggers increased phosphorylation of STAT1 and up-regulates expression of VCAM1 and ICAM1 (PubMed:23892569). Promotes leukocyt |
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| Size | 0.005 mg, 0.02 mg, 0.1 mg, 0.25 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | [Activation-inducible TNF-related ligand; Glucocorticoid-induced TNF-related ligand; hGITRL] |
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| Gene, Accession, CAS # | TNFSF18, Gene ID: 8995, Accession: NP_005083.2 |
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| Catalog # | MBS969353 |
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| Order / More Info | Recombinant Human Tumor necrosis factor ligand superfamily member 18 protein (TNFSF18) (Active) from MYBIOSOURCE INC. |
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| Product Specific References | n/a |
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