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| Product Name | Human CCM-2 |
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| Description | MW: 51.0 kDa. Purity >95% by SDS-PAGE & silver stain. Cerebral cavernous malformations (CCMs) are sporadically acquired or inherited vascular lesions of the central nervous system consisting of clusters of dilated thin-walled blood vessels that predispose individuals to seizures and stroke. Familial CCM is caused by mutations in KRIT1 (CCM1) or in malcavernin (CCM2). The roles of the CCM proteins in the pathogenesis of the disorder remain largely unknown. It was shown that the CCM1 gene product, |
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| Size | 0.02 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | [Recombinant Human CCM2; Cerebral cavernous malformations1 2 protein] |
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| Gene, Accession, CAS # | CCM-2, Gene ID: 83605, Accession: NP_001025006.1 |
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| Catalog # | MBS691545 |
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| Order / More Info | Human CCM-2 from MYBIOSOURCE INC. |
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| Product Specific References | 1. Plummer et al, Curr Neurol Neurosci Rep 5 (2005) 2. Dashti et al, Neurosurg Focus 21 (2006) 3. Revencu N and Vikkula M, J Med Genet 43 (2006) 4. Yadla et al, S, Neurosurg Focus 29 (2010) 5. Verlaan DJ et al, Neurology 26 (2002) |
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