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| Product Name | PKCa, Active, Recombinant, Human (Protein Kinase C alpha, Protein Kinase C alpha Type) |
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| Description | Purity ~90% (SDS-PAGE). Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. PKC-alpha has been reported to play roles in many different cellular processes, such as cell adhesion, cell transformation, cell cycle checkpoint, and cell volume control. Coussens defined a new family of PKC-related genes and termed alpha, beta, and gamma (1). Latos-Bielenska refined the assignment of PRKCA1 to 17q22-q23.2 (2). Braz identified PKC-alpha as a fundamental regulator of cardiac contractility and Ca(2+) handling in myocytes in study of knockout mice (3). Source: Recombinant protein corresponding to active human PKCa, expressed in Baculovirus (Sf9 insect cells). Mol |
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| Size | 5ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | pkcalpha, pkc-alpha, pkca, pkc-a, pkc a, Active PKCa, PKCa,PKC alpha, human PKCa, active kinase, active kinases, PKC, recombinant PKCa, recombinant PKC, kinase activity assay, protein kinase |
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| Gene, Accession, CAS # | PKCA, Gene ID: 5578, SwissProt: P17252 |
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| Catalog # | 220171 |
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| Order / More Info | PKCa, Active, Recombinant, Human (Protein Kinase C alpha, Protein Kinase C alpha Type) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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