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| Product Name | Importazole (IPZ, N-(1-Phenylethyl)-2-pyrrolidin-1-ylquinazolin-4-amine, Importin-b Inhibitor) |
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| Description | Purity ~98% (HPLC). A cell-permeable diaminoquinazoline compound that selectively blocks importin-b-mediated nuclear import of NLS- (nuclear localization signal) bearing cargos (IC50=15uM against Ca+2-induced NFAT nuclear import in HEK293 cells) in a reversible manner without affecting transportin-dependent nuclear import of M9 signal-containing cargos or CRM1-mediated nuclear export. Formula: C20H22N4 Molecular Weight: 318.4 Solubility: DMSO (25mg/ml, clear, colorless solution) |
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| Size | 10mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | 217455 |
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| Order / More Info | Importazole (IPZ, N-(1-Phenylethyl)-2-pyrrolidin-1-ylquinazolin-4-amine, Importin-b Inhibitor) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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