| 产品详情 |
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| Antigenic Specificity | Nerve Growth Factor Receptor (NGFR) (Cytoplasmic Domain) |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | rat, mouse |
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| Isotype | n/a |
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| Format | serum |
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| Size | 100 µL |
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| Concentration | n/a |
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| Applications | Immunohistochemistry (IHC),Western Blotting (WB) |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Function: Low affinity receptor which can bind to NGF, BDNF, NT-3, and NT-4. Can mediate cell survival as well as cell death of neural cells.Subunit: Homodimer, disulfide-linked. Interacts with p75NTR-associated cell death executor. Interacts with NGFRAP1/BEX3. Interacts with TRAF2, TRAF4, TRAF6, PTPN13 and RANBP9. Interacts through TRAF6 with SQSTM1 which bridges NGFR to NTRK1. Interacts with BEX1. Interacts with ARMS and NTRK1. Can form a ternary complex with NTRK1 and ARMS and this complex is affected by the expression levels of ARMS. An increase in ARMS expression leads to a decreased association of NGFR and NTRK1. Interacts with LINGO1.Subcellular location: Membrane, Single-pass type I membrane protein. Also known as: Low-affinity nerve growth factor receptor, NGF receptor, Gp80-LNGFR, p75 ICD, Low affinity neurotrophin receptor p75NTR, p75, LNGFR, p75NTR, RNNGFRR. |
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| Immunogen | A synthetic peptide from the cytoplasmic domain of rat p75NTR conjugated to an immunogenic carrier protein was used as the antigen. The antigen is homologous in mouse. |
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| Other Names | ngfr|wu:fb38c02|wu:fc10h01|CD271|Gp80-LNGFR|TNFRSF16|p75(NTR)|p75NTR|LNGFR|RNNGFRR|Tnfrsf16|p75|NRH1b|fullback|nrh1|p75ntr|tnfrsf16|p75NGFR |
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| Gene, Accession # | Gene ID: 18053,24596 |
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| Catalog # | ABIN350708 |
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| Price | |
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| Order / More Info | Nerve Growth Factor Receptor (NGFR) (Cytoplasmic Domain) Antibody from ANTIBODIES-ONLINE GmbH |
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| Product Specific References | PubMed: 15378608, 11150334, 9305641, 1446821, 3027580, 16498402 |
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