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Antigenic Specificity | Nerve Growth Factor Receptor (NGFR) (Cytoplasmic Domain) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | rat, mouse, human, chicken |
Isotype | n/a |
Format | serum |
Size | 100 µL |
Concentration | n/a |
Applications | Immunohistochemistry (IHC),Western Blotting (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Function: Low affinity receptor which can bind to NGF, BDNF, NT-3, and NT-4. Can mediate cell survival as well as cell death of neural cells.Subunit: Homodimer, disulfide-linked. Interacts with p75NTR-associated cell death executor. Interacts with NGFRAP1/BEX3. Interacts with TRAF2, TRAF4, TRAF6, PTPN13 and RANBP9. Interacts through TRAF6 with SQSTM1 which bridges NGFR to NTRK1. Interacts with BEX1. Interacts with ARMS and NTRK1. Can form a ternary complex with NTRK1 and ARMS and this complex is affected by the expression levels of ARMS. An increase in ARMS expression leads to a decreased association of NGFR and NTRK1. Interacts with LINGO1.Subcellular location: Membrane, Single-pass type I membrane protein. Also known as: Low-affinity nerve growth factor receptor, NGF receptor, Gp80-LNGFR, p75 ICD, Low affinity neurotrophin receptor p75NTR, p75, LNGFR, p75NTR, RNNGFRR. |
Immunogen | A synthetic peptide from the cytoplasmic domain of chicken p75NTR (low affinity NGF receptor, p75, LNGFR, p75NTR) conjugated to an immunogenic carrier protein was used as the antigen. |
Other Names | ngfr|wu:fb38c02|wu:fc10h01|CD271|Gp80-LNGFR|TNFRSF16|p75(NTR)|p75NTR|LNGFR|RNNGFRR|Tnfrsf16|p75|NRH1b|fullback|nrh1|p75ntr|tnfrsf16|p75NGFR |
Gene, Accession # | Gene ID: 4804,18053,24596 |
Catalog # | ABIN572036 |
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Order / More Info | Nerve Growth Factor Receptor (NGFR) (Cytoplasmic Domain) Antibody from ANTIBODIES-ONLINE GmbH |
Product Specific References | n/a |
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