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Antigenic Specificity | TGF-beta Activated Kinase 1/MAP3K7 Binding Protein 2 (TAB2) |
Clone | 3B5 |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1 |
Format | ascites |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blotting (WB),Flow Cytometry (FACS),ELISA |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The protein encoded by this gene is an activator of MAP3K7/TAK1, which is required for for the IL-1 induced activation of nuclear factor kappaB and MAPK8/JNK. This protein forms a kinase complex with TRAF6, MAP3K7 and TAB1, thus serves as an adaptor linking MAP3K7 and TRAF6. This protein, TAB1, and MAP3K7 also participate in the signal transduction induced by TNFSF11/RANKl through the activation of the receptor activator of NF-kappB (TNFRSF11A/RANK), which may regulate the development and function of osteoclasts.Synonyms: CHTD2, FLJ21885, KIAA0733, MAP3K7IP2, TAB2 |
Immunogen | Purified recombinant fragment of human TAB2 expressed in E. Coli. |
Other Names | CHTD2|MAP3K7IP2|1110030N06Rik|A530078N03Rik|Map3k7ip2|mKIAA0733|map3k7ip2|zgc:77446 |
Gene, Accession # | Gene ID: 23118 |
Catalog # | ABIN967128 |
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Order / More Info | TGF-beta Activated Kinase 1/MAP3K7 Binding Protein 2 (TAB2) Antibody from ANTIBODIES-ONLINE GmbH |
Product Specific References | PubMed: 16384851, 16913963, 20493459, 17047224 |
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