产品详情 |
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Antigenic Specificity | Toll-Like Receptor Adaptor Molecule 2 (TICAM2) (aa 2-29) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | unconjugated |
Size | 50 µL |
Concentration | n/a |
Applications | Western Blotting (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | TRAM functions in LPS-TLR4 signaling to regulate the MYD88-independent pathway during the innate immune response to LPS. It is also involved in IL-1-triggered NF-kappaB activation, functioning upstream of IRAK1, IRAK2, TRAF6 and IKBKB. TRAM physically bridges TLR4 and TICAM-1 and functionally transmits LPS-TRL4 signal to TICAM-1. It is expressed in spleen, prostate, testis, uterus, small intestine, colon, peripheral blood leukocytes, heart, placenta, lung, liver, skeletal muscle and pancreas. |
Immunogen | Synthetic peptide corresponding to aa 2-29 (G2IGKSKINSCPLSLSWGKRHSVDTSPGY29) of human TRAM. |
Other Names | MyD88-4|TICAM-2|TIRAP3|TIRP|TRAM|B430113A10|Tirp|Trif |
Gene, Accession # | Gene ID: 353376 |
Catalog # | ABIN1169199 |
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Order / More Info | Toll-Like Receptor Adaptor Molecule 2 (TICAM2) (aa 2-29) Antibody from ANTIBODIES-ONLINE GmbH |
Product Specific References | PubMed: 17138826 |
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