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| Product Name | HuS1, 1-280aa, Human, His tag, E Coli |
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| Description | MW: 33.8 kDa (300aa), confirmed by MALDI-TOF. Purity >95% by SDS-PAGE. HuS1 is a component of an evolutionarily conserved, genotoxin-activated checkpoint complex. This protein associates with Rad9 and Rad1 to form the 9-1-1 (RAD9-RAD1-HuS1) complex, which localizes to DNA lesions and promotes DNA damage signaling and repair or apoptosis, cell cycle arrest. The trimeric complex is structurally similar to the proliferating cell nuclear antigen (PCNA) sliding clamp and interacts with Rad17 as a cla |
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| Size | 0.01 mg, 0.05 mg |
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| Concentration | 0.25mg/ml (determined by Bradford assay) |
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| Applications | SDS-PAGE |
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| Other Names | [checkpoint protein HuS1] |
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| Gene, Accession, CAS # | HuS1, Gene ID: 3364, Accession: NP_004498 |
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| Catalog # | MBS203967 |
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| Order / More Info | HuS1, 1-280aa, Human, His tag, E Coli from MYBIOSOURCE INC. |
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| Product Specific References | Weiss RS., et al (2009) Proc Natl Acad Sci u S A. 106 (50):21282-7.; Roos-Mattjus P., et al (2002) J Biol Chem. 15;277 (46):43809-12. |
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