| 产品详情 |
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| Antigenic Specificity | HIF1a |
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| Clone | polyclonal |
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| Host Species | Goat |
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| Reactive Species | human, mouse, rat, bovine, canine, chicken/avian, donkey, feline, goat, guinea pig, hamster, horse, porcine, rabbit, sheep, simian, other |
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| Isotype | n/a |
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| Format | immunoaffinity purified |
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| Size | 600 µg |
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| Concentration | 3 mg/ml |
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| Applications | WB |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Goat polyclonal to alpha subunit of transcription factor hypoxia-inducible factor-1 (HIF-1), which is a heterodimer composed of an alpha and a beta subunit. HIF-1 functions as a master regulator of cellular and systemic homeostatic response to hypoxia by activating transcription of many genes, including those involved in apoptosis, angiogenesis, energy metabolism, and other genes whose protein products increase oxygen delivery or facilitate metabolic adaptation to hypoxia. HIF-1 thus plays an essential role in tumour angiogenesis, embryonic vascularization, and pathophysiology of ischemic disease. Detects HIF1a in transfected cells and a band of approximately 120 kDa by Western blot in cell lysates. |
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| Immunogen | Purified recombinant peptide derived from within residues 780 aa to the C-terminus of human HIF1a produced in E. coli. |
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| Other Names | alpha subunit (basic helix-loop-helix transcription factor), ARNT interacting protein, basic-helix-loop-helix-PAS protein MOP1, bHLHe78, class E basic helix-loop-helix protein 78, HIF-1alpha, HIF1, HIF1-ALPHA, HIF1a, hypoxia inducible factor 1, hypoxia-inducible factor 1 alpha isoform I.3, hypoxia-inducible factor 1, hypoxia-inducible factor 1-alpha, member of PAS protein 1, member of PAS superfamily 1, MOP1, PASD8, PAS domain-containing protein 8 |
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| Gene, Accession # | HIF1a, Gene ID: 3091 |
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| Catalog # | AB0112-200 |
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| Price | |
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| Order / More Info | HIF1a Antibody from SICGEN ANTIBODIES |
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| Product Specific References | 1. Rodrigues T, Matafome P, Sereno J, et al. Sci Rep. 2017 May. PMID:28490763, 2. Sacramento JF, Ribeiro MJ, Rodrigues T, et al. Respir Physiol Neurobiol. 2016 Jul. PMID:26993367, 3. Ferreira JV, Soares AR, Ramalho JS, et al. Scientific Reports 5, May 2015. PMID: 25958982 |
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