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| Product Name | HLA-DOB, 27-224aa, Human, His tag, E Coli (Denatured) |
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| Description | MW: 25.2 kDa (222aa). Purity >95% by SDS-PAGE. HLA-DOB belongs to the HLA class II beta chain paralogues. This class II molecule is a heterodimer consisting of an alpha (DOA) and a beta chain (DOB), both anchored in the membrane. It is located in intracellular vesicles. DO suppresses peptide loading of MHC class II molecules by inhibiting HLA-DM. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The beta chain is approximately 26-28 |
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| Size | 0.1 mg, 0.5 mg |
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| Concentration | 1 mg/ml (determined by Bradford assay) |
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| Applications | SDS-PAGE |
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| Other Names | [Major histocompatibility complex class II DO beta; Major histocompatibility complex; class II; DO beta; DOB] |
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| Gene, Accession, CAS # | HLA-DOB, Gene ID: 3112, Accession: NP_002111 |
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| Catalog # | MBS205672 |
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| Order / More Info | HLA-DOB, 27-224aa, Human, His tag, E Coli (Denatured) from MYBIOSOURCE INC. |
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| Product Specific References | Naruse T.K., et al. (2002) Tissue Antigens. 59:512-519; Beck S., et al. (1996) J. Mol. Biol. 255:1-13; |
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