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| Product Name | HLA-DOB, Recombinant, Human, aa27-224, His-Tag |
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| Description | Purity ~95% (SDS-PAGE). HLA-DOB belongs to the HLA class II beta chain paralogues. This class II molecule is a heterodimer consisting of an alpha (DOA) and a beta chain (DOB), both anchored in the membrane. It is located in intracellular vesicles. DO suppresses peptide loading of MHC class II molecules by inhibiting HLA-DM. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The beta chain is ~26-28kD and its gene contains 6 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, exon 4 encodes the transmembrane domain and exon 5 encodes the cytoplasmic tail. Source: Recombinant protein corresponding to aa27-224 from human HLA-DOB, fused to His-tag at N-terminus, expressed in E.coli. Molecular Weight: ~25.2kD (222aa) Applications: Suitable for use in SDS-PAGE. |
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| Size | 100ug, 500ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | HLA-DOB, Recombinant, Human, aa27-224, His-Tag (Major Histocompatibility Complex, Class II, DO beta) |
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| Gene, Accession, CAS # | Accession: NP_002111 |
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| Catalog # | 218224 |
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| Order / More Info | HLA-DOB, Recombinant, Human, aa27-224, His-Tag from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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