| 产品详情 |
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| Product Name | Hexokinase 4, Control Peptide |
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| Description | Control peptide for H2040-51M. Hexokinase catalyzes the first step of several metabolic pathways by converting D-hexose to D-hexose-6-P. Hexokinase is an allosteric enzyme inhibited by its products glucose-6-phosphate. At least 4 related hexokinase isoforms (HXKI-III; HXK-IV also known as Glucokinase) have been cloned and characterized. Hexokinases (~100kD for HXK1-III; HXKIV lacks the N-terminal domains and is ~50kD) are outer mitochondrial membrane proteins. The N-terminus, containing the mitochondrial target sequence, and the C- terminal has high sequence homology among various isoforms. The catalytic activity is associated with the C-terminus and other regulatory functions are controlled by the N-terminus. HXK4 (mouse 465aa, isoforms 1) isoforms are produced by use of alternative promoters. The use of alternative promoters apparently enables the type IV hexokinase gene to be regulated by insulin in the liver and glucose in the beta cell. This may constitute an important feedback lo |
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| Size | 100ug |
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| Concentration | n/a |
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| Applications | ELISA |
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| Other Names | Hexokinase 4, Control Peptide (Glucokinase, Hexokinase Type IV, HK IV, Hexokinase-4, HK4, Hexokinase-D, GCK) |
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| Gene, Accession, CAS # | SwissProt: P52792 |
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| Catalog # | H2040-51N |
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| Price | |
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| Order / More Info | Hexokinase 4, Control Peptide from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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