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| Product Name | CYR61, Recombinant, Human, aa25-381, His-SUMO-Tag (Protein CYR61) |
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| Description | Purity ~90% (SDS-PAGE). Promotes cell proliferation, chemotaxis, angiogenesis and cell adhesion. Appears to play a role in wound healing by up-regulating, in skin fibroblasts, the expression of a number of genes involved in angiogenesis, inflammation and matrix remodeling including VEGA-A, VEGA-C, MMP1, MMP3, TIMP1, uPA, PAI-1 and integrins alpha-3 and alpha-5. CYR61-mediated gene regulation is dependent on heparin-binding. Down-regulates the expression of alpha-1 and alpha-2 subunits of collagen type-1. Promotes cell adhesion and adhesive signaling through integrin alpha-6/beta-1, cell migration through integrin alpha-v/beta-5 and cell proliferation through integrin alpha-v/beta-3. Source: Recombinant protein corresponding to aa25-381 from human CYR61, fused to His-SUMO-Tag at N-terminal expressed in E. coli. Molecular Weight: ~55.4kD AA |
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| Size | 10ug, 50ug, 100ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | CCN family member 1, Cysteine-rich angiogenic inducer 61 Insulin-like growth factor-binding protein 10, IBP-10, IGF-binding protein 10, IGFBP-10, Protein GIG1 |
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| Gene, Accession, CAS # | SwissProt: O00622 |
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| Catalog # | 372959 |
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| Order / More Info | CYR61, Recombinant, Human, aa25-381, His-SUMO-Tag (Protein CYR61) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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