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| Product Name | IL-17A, Recombinant, Human, Animal Free (IL-17, Interleukin 17, CTLA-8) |
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| Description | Purity ~98% (SDS-PAGE gel, HPLC). The originally described IL-17 protein, now known as IL-17A, is a homodimer of two 136aa chains, secreted by activated T-cells that act on stromal cells to induce production of proinflammatory and hematopoietic bioactive molecules. Today, IL-17 represents a family of structurally-related cytokines that share a highly conserved C-terminal region but differ from one another in their N-terminal regions and in their distinct biological roles. The six known members of this family, IL-17A through IL-17F, are secreted as homodimers. IL-17A exhibits cross-species bioactivity between human and murine cells. Recombinant human IL-17A is a 31kD disulfide-linked homodimer of two 136aa polypeptide chains. Source: Recombinant protein corresponding to human IL-17A, expressed in E. coli. Biological Activity: Assay #1: Determined by the dose-dependent induction of IL-6 in primary human foreskin fibroblast. The expected ED50 is <2.0ng/ml, corresponding to a specific acti |
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| Size | 5ug, 25ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | 208646 |
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| Order / More Info | IL-17A, Recombinant, Human, Animal Free (IL-17, Interleukin 17, CTLA-8) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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