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| Product Name | Il23a, Recombinant, Mouse, aa22-196, His-Tag (Interleukin-23 Subunit alpha) |
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| Description | Purity ~90% (SDS-PAGE). Associates with IL12B to form the IL-23 interleukin, a heterodimeric cytokine which functions in innate and adaptive immunity. IL-23 may constitute with IL-17 an acute response to infection in peripheral tissues. IL-23 binds to a heterodimeric receptor complex composed of IL12RB1 and IL23R, activates the Jak-Stat signaling cascade, stimulates memory rather than naive T-cells and promotes production of proinflammatory cytokines. IL-23 induces autoimmune inflammation and thus may be responsible for autoimmune inflammatory diseases and may be important for tumorigenesis. Source: Recombinant protein corresponding to aa22-196 from mouse Il23a, fused to His-Tag at N-terminal, expressed in E. coli. Molecular Weight: ~23.7kD AA |
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| Size | 10ug, 50ug, 100ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | IL-23 subunit alpha, IL-23-A, Interleukin-23 subunit p19, IL-23p19 |
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| Gene, Accession, CAS # | SwissProt: Q9EQ14 |
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| Catalog # | 373815 |
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| Order / More Info | Il23a, Recombinant, Mouse, aa22-196, His-Tag (Interleukin-23 Subunit alpha) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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