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| Product Name | Relaxin-2 (human) |
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| Description | Purity >90% by SDS-PAGE. A Chain Endogenous ligand for the orphan G-protein-coupled receptor LGR7. Insulin-like hormone. Hormonal signaling by relaxin family peptides is important for the regulation of mammary gland development, reproductive tract remodeling, testis descent, neurotransmission, cardiovascular homeostasis, and osmoregulation. Among the seven human relaxin family peptides (relaxin1, relaxin2, INSL3/RLF, INSL4/EPIL, INSL5/RIF2, INSL6/RIF1, and INSL7/relaxin3). Recent studies have characterized two GPCRs, LGR7 and LGR8, as relaxin receptors. Subsequent studies have shown that LGR7 and LGR8 are also cognate receptors for relaxin family peptides INSL7/relaxin3 and INSL3, respectively. In addition, INSL7/relaxin3 signals through two orphan GPCRs, GPCR135 and GPCR142. |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | LS-H11225 |
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| Order / More Info | Relaxin-2 (human) from LIFESPAN BIOSCIENCES INC. |
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| Product Specific References | n/a |
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