| 产品详情 |
| Edit |   |
|---|
| Product Name | LFM-A13 |
|---|
| Description | MW: 360. Purity 98% (TLC: 2:8 CH3OH:CH2Cl2; Rf=0.53); NMR (Conforms). BTK InhibitorPotent, selective inhibitor of the NGF receptor tyrosine kinase A (TrkA) (IC50 = 2 nM). Displays >100-fold selectivity over a range of other kinases. Blocks TrkA-mediated gH2AX production2 and apoptosis3 in TrkA-overexpressing cells. Cell permeable.Scientific Background: Potent and selective inhibitor of Bruton's tyrosine kinase (BTK). Inhibits recombinant BTK wi |
|---|
| Size | 5 mg, 25 mg |
|---|
| Concentration | n/a |
|---|
| Applications | n/a |
|---|
| Other Names | [GW-441756; 1,3-Dihydro-3-[(1-methyl-1H-indol-3--yl)methylene]-2H-pyrrolo[3,2-b]pyridin-2-one; 2-Cyano-N-(2,5-dibromophenyl)-3-hydroxy-2-butenamide] |
|---|
| Gene, Accession, CAS # | CAS: 62004-35-7 |
|---|
| Catalog # | MBS515028 |
|---|
| Price | |
|---|
| Order / More Info | LFM-A13 from MYBIOSOURCE INC. |
|---|
| Product Specific References | 1. ER Wood et al. Bioorg. Med. Chem. Lett. 2004 14:953 2. EJ Jung et al. Exp. Mol. Med. 2008 40:276 3. EJ Wood et al. Mol. Cells Lett. 2008 26:12 |
|---|
| 产品资料 |
|
|