| 产品详情 |
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| Product Name | Thiostrepton |
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| Description | Purity > 99% by HPLC. Thiostrepton is a macrocyclic antibiotic incorporating thiazoles and other atypical amino acids. Patented in 1961, thiostrepton has been used as an antibiotic and acts by binding to ribosomes to prevent the binding of the EF-G elongation factor and GTP to the 50S riobsomal subunit. Thiostrepton is an inducer of tipA, a gene that controls the bacterial transcription regulators, TipAL and TipAS, members of the MerR proteins that are central regulators in multidrug resistance. Closely related to siomycin, a recently discovered inhibitor of oncogenic transcription factor-FoxM1. DMSO and DMF, partially soluble in methanol and ethanol while poorly soluble in water |
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| Size | 5mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | Thiostrepton (Bryamycin, Thiactin, Alaninamide, Antibiotic X 146, Antibiotic A 8506, Antibiotic 6761-31) |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | T3792-12 |
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| Order / More Info | Thiostrepton from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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| 产品资料 |
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