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| Product Name | Recombinant Human Neuroepithelial cell-transforming gene 1 protein |
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| Description | 1-542aa; Full Length of Isoform 2. MW: 77.8kD. Purity >90% as determined by SDS-PAGE. Acts as guanine nucleotide exchange factor (GEF) for RhoA GTPase. May be involved in activation of the SAPK/JNK pathway Stimulates genotoxic stress-induced RHOB activity in breast cancer cells leading to their cell death. |
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| Size | 0.01 mg (E-Coli), 0.05 mg (E-Coli), 0.1 mg (E-Coli), 0.2 mg (E-Coli), 0.5 mg (E-Coli) |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | [Proto-oncogene p65 Net1; Rho guanine nucleotide exchange factor 8] |
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| Gene, Accession, CAS # | NET1, Gene ID: 10276, Accession: NP_001040625.1 |
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| Catalog # | MBS1406386 |
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| Order / More Info | Recombinant Human Neuroepithelial cell-transforming gene 1 protein from MYBIOSOURCE INC. |
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| Product Specific References | Isolation of a novel oncogene, NET1, from neuroepithelioma cells by expression cDNA cloning.Chan A.M.-L., Takai S., Yamada K., Miki T.Oncogene 12:1259-1266(1996) The activity of guanine exchange factor NET1 is essential for transforming growth factor-beta-mediated stress fiber formation.Shen X., Li J., Hu P.P.-C., Waddell D., Zhang J., Wang X.-F.J. Biol. Chem. 276:15362-15368(2001) A quantitative atlas of mitotic phosphorylation.Dephoure N., Zhou C., Villen J., Beausoleil S.A., Bakalarski C.E., |
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