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| Product Name | HMGCL, 28-325aa, Human, His tag, E Coli (Denatured) |
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| Description | MW: 34.2 kDa (323aa). Purity >85% by SDS-PAGE. HMGCL, also known as hydroxymethylglutaryl-CoA lyase, is a mitochondrial matrix protein that belongs to the HMG-CoA lyase family. It exists as a homodimer and participates in leucine catabolism and ketogenesis, the hepatic synthesis of ketone bodies that, during fasting, provide a major source of energy for heart, brain and kidney. More specifically, it catalyzes the final step of these processes, the cleavage of 3-hydroxy-3-methylglutaryl-CoA to ac |
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| Size | 0.1 mg, 0.5 mg |
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| Concentration | 1.0 mg/ml (determined by Bradford assay) |
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| Applications | SDS-PAGE |
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| Other Names | [Hydroxymethylglutaryl-CoA lyase; 3-hydroxy-3-methylglutarate-CoA lyase; HL; HMG-CoA lyase; Hydroxymethylglutaryl-CoA lyase mitochondrial] |
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| Gene, Accession, CAS # | HMGCL, Gene ID: 3155, Accession: NP_000182 |
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| Catalog # | MBS204769 |
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| Order / More Info | HMGCL, 28-325aa, Human, His tag, E Coli (Denatured) from MYBIOSOURCE INC. |
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| Product Specific References | Cardoso M.L. et al. (2004) Mol. Genet. Metab. 82: 334-338.; Wang S.P et al. (1996) Genomics 33: 99-104. |
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