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| Product Name | Recombinant Human Nucleoside diphosphate kinase A |
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| Description | 2-152aa; Full Length. MW: 44.4kD. Purity >90% as determined by SDS-PAGE. Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate. Possesses nucleoside-diphosphate kinase, serine/threonine-specific protein kinase, geranyl and farnesyl pyrophosphate kinase, histidine protein kinase and 3'-5' exonuclease activities. Involved in cell proliferatio |
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| Size | 0.01 mg, 0.05 mg, 0.1 mg, 0.2 mg, 0.5 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | [Granzyme A-activated DNase; GAAD; Metastasis inhibition factor nm23; NM23-H1; Tumor metastatic process-associated protein] |
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| Gene, Accession, CAS # | NME1, Gene ID: 4830, Accession: NP_000260.1 |
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| Catalog # | MBS717047 |
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| Order / More Info | Recombinant Human Nucleoside diphosphate kinase A from MYBIOSOURCE INC. |
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| Product Specific References | Reduced Nm23/Awd protein in tumour metastasis and aberrant Drosophila development.Rosengard A.M., Krutzsch H.C., Shearn A., Biggs J.R., Barker E., Margulies I.M.K., King C.R., Liotta L.A., Steeg P.S.Nature 342:177-180(1989) Nucleoside diphosphate kinase from human erythrocytes. Structural characterization of the two polypeptide chains responsible for heterogeneity of the hexameric enzyme.Gilles A.-M., Presecan E., Vonica A., Lascu I.J. Biol. Chem. 266:8784-8789(1991) Mutation in the nm23 gene is |
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