| 产品详情 |
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| Antigenic Specificity | APP / Beta Amyloid Precursor |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | mouse, human |
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| Isotype | n/a |
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| Format | biotin conjugate |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | IHC, IP, WB |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | APP / Beta Amyloid Precursor Antibody (Biotin) LS-C523341. Specificity: Reacts with mouse and human APP. On Western blots, this antibody identifies a specific band representing the full-length protein at ~100kD, and a band at ~10-12kD representing the C99 C-terminal cleavage fragment. A major non-specific band has been observed at ~50kD in mouse brain homogenates. Reactivity has been confirmed with APLP2 (amyloid precursor-like protein 2) -/- knock-out and wild type mouse brain homogenates, and APP695 C99 (C-terminal fragment)-transfected HEK293 cell lysates by Western blotting. Negative control tests with APP -/- knock-out and APP/APLP2 double knock-out mice have confirmed the specificity of this antibody; neither of the target bands were identified in these test samples. Reactivity has also been confirmed with human Alzheimer's brain tissue by immunohistochemistry. |
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| Immunogen | Synthetic peptide derived from the C-terminal region of the human and mouse amyloid-beta precursor protein (APP695). |
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| Other Names | APP, ABPP, A4, ABETA, AD1, Alzheimer disease, Amyloid beta, Beta-amyloid peptide, APPI, Beta amyloid, CVAP, AAA, PN2, PreA4, Amyloid beta A4 protein, Peptidase nexin-II, CTFgamma, PN-II, Protease nexin-II |
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| Gene, Accession # | APP, Gene ID: 351 |
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| Catalog # | LS-C523341 |
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| Price | |
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| Order / More Info | APP / Beta Amyloid Precursor Antibody from LIFESPAN BIOSCIENCES INC. |
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| Product Specific References | n/a |
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