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| Product Name | A 83-01 (3-(6-Methyl-2-pyridinyl)-N-phenyl-4-(4-quinolinyl)-1H-pyrazole-1-carbothioamide) |
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| Description | Purity ~98% (HPLC). A selective inhibitor of TGF-beta type I receptor ALK5 kinase, type I activin/nodal receptor ALK4 and type I nodal receptor ALK7 (IC50 values are 12, 45 and 7.5nM respectively). Blocks phosphorylation of Smad2 and inhibits TGF beta-induced epithelial-to-mesenchymal transition. Helps maintain homogeneity and long-term in vitro self-renewal of human induced pluripotent stem cells (iPSCs). |
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| Size | 1mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 3-(6-Methyl-2-pyridinyl)-N-phenyl-4-(4-quinolinyl)-1H-pyrazole-1-carbothioamide |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | A0000-08 |
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| Order / More Info | A 83-01 (3-(6-Methyl-2-pyridinyl)-N-phenyl-4-(4-quinolinyl)-1H-pyrazole-1-carbothioamide) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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