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| Product Name | MIS RII, Fc Chimera, Recombinant, Human |
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| Description | Purity ≥ 90%, as determined by SDS-PAGE under reducing conditions and visualized by silver stain. Endotoxin ≤ 1EU per 1ug of protein (LAL method). Human MIS RII (Mullerian inhibiting substance type II receptor), also known as AMHRII (anti-Mullerian hormone type II receptor), is an 82kD serine/threonine receptor with a single transmembrane domain that belongs to the family of type II receptors of the TGF-Beta superfamily (1). The MIS RII precursor is 573 amino acids (aa) in length, with a 17 aa signal sequence, a 127 aa extracellular region that also contains two potential N-linked glycosylation sites, a 26 aa transmembrane region, and a 403 aa cytoplasmic region that contains the serine/threonine kinase domain (1). Human MIS RII shares 82%, 78%, and 77% aa sequence identity with rabbit, mouse, and rat MIS RII, respectively. It is expressed in the mesenchyme surrounding the fetal Mullerian duct, in fetal and postnatal granulosa cells, and in Sertoli cells (1-6). MIS RII is a receptor fo |
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| Size | 50ug |
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| Concentration | n/a |
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| Applications | ELISA |
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| Other Names | MIS RII, Fc Chimera, Recombinant, Human (Mullerian Inhibiting Substance Type II Teceptor, AMHRII, anti-Mullerian Hormone Type II Receptor) |
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| Gene, Accession, CAS # | SwissProt: Q16671 |
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| Catalog # | M3955-30 |
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| Order / More Info | MIS RII, Fc Chimera, Recombinant, Human from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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