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| Product Name | DSCR1 isoform b, 1-117aa, Human, E Coli |
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| Description | MW: 13kDa (117aa), confirmed by MALDI-TOF. Purity >90% by SDS-PAGE. The Down's syndrome candidate region 1 (DSCR1) protein, encoded by a gene located in the human chromosome 21, interacts with calcineurin and is overexpressed in Down's syndrome patients. DSCR1 Inhibits calcineurin-dependent transcriptional responses by binding to the catalytic domain of calcineurin A, possibly affecting central nervous system development. DSCR isoform b is shorter at the N-terminus compared to isoform a. Recombi |
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| Size | 0.1 mg, 0.5 mg |
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| Concentration | 1 mg/ml (determined by Bradford assay) |
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| Applications | SDS-PAGE |
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| Other Names | [Down syndrome candidate region 1; Down syndrome candidate region 1; Down syndrome critical region protein 1; adapt78 protein; calcipressin 1; Calcipressin 1 isoform b; Down syndrome candidate region 1] |
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| Gene, Accession, CAS # | DSCR1, Gene ID: 1827, Accession: NP_981962 |
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| Catalog # | MBS203113 |
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| Order / More Info | DSCR1 isoform b, 1-117aa, Human, E Coli from MYBIOSOURCE INC. |
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| Product Specific References | Hesser BA., et al. (2004) Blood. 104 (1):149-58; Harris CD., et al. (2007) FEBS J. 274 (7):1715-24.; |
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