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| Product Name | ESR2, Recombinant, Human, aa2-530, His-Tag (Estrogen Receptor beta) |
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| Description | Purity ~90% (SDS-PAGE). Nuclear hormone receptor. Binds estrogens with an affinity similar to that of ESR1, and activates expression of reporter genes containing estrogen response elements (ERE) in an estrogen-dependent manner. Isoform beta-cx lacks ligand binding ability and has no or only very low ERE binding activity resulting in the loss of ligand-dependent transactivation ability. DNA-binding by ESR1 and ESR2 is rapidly lost at 37°C in the absence of ligand while in the presence of 17 beta-estradiol and 4-hydroxy-tamoxifen loss in DNA-binding at elevated temperature is more gradual. Source: Recombinant protein corresponding to aa2-530 from human ESR2, fused to His-Tag at N-terminal, expressed in E. coli. Molecular Weight: ~63.1kD AA |
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| Size | 10ug, 50ug, 100ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | Nuclear receptor subfamily 3 group A member 2 |
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| Gene, Accession, CAS # | SwissProt: Q92731 |
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| Catalog # | 373229 |
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| Order / More Info | ESR2, Recombinant, Human, aa2-530, His-Tag (Estrogen Receptor beta) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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