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| Product Name | Recombinant Human Serine/threonine-protein kinase STK11 |
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| Description | 1-430aa; Full Length of Mature Protein. MW: 64.1kD. Purity >90% as determined by SDS-PAGE. Tumor suppressor serine/threonine-protein kinase that controls the activity of AMP-activated protein kinase (AMPK) family members, thereby playing a role in various processes such as cell metabolism, cell polarity, apoptosis and DNA damage response. Acts by phosphorylating the T-loop of AMPK family proteins, thus promoting their activity: phosphorylates PRKAA1, PRKAA2, BRSK1, BRSK2, MARK1, MARK2, MARK3, MA |
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| Size | 0.01 mg (E-Coli), 0.05 mg (E-Coli), 0.1 mg (E-Coli), 0.2 mg (E-Coli), 0.5 mg (E-Coli) |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | [Liver kinase B1; LKB1; hLKB1; Renal carcinoma antigen NY-REN-19] |
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| Gene, Accession, CAS # | STK11, Gene ID: 6794, Accession: NP_000446.1 |
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| Catalog # | MBS1397121 |
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| Order / More Info | Recombinant Human Serine/threonine-protein kinase STK11 from MYBIOSOURCE INC. |
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| Product Specific References | Peutz-Jeghers syndrome is caused by mutations in a novel serine threonine kinase.Jenne D.E., Reimann H., Nezu J., Friedl W., Loff S., Jeschke R., Mueller O., Back W., Zimmer M.Nat. Genet. 18:38-43(1998) Low frequency of somatic mutations in the LKB1/Peutz-Jeghers syndrome gene in sporadic breast cancer.Bignell G.R., Barfoot R., Seal S., Collins N., Warren W., Stratton M.R.Cancer Res. 58:1384-1386(1998) Complete sequencing and characterization of 21,243 full-length human cDNAs.Ota T., Suzuki Y., |
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