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Antigenic Specificity | Neurotrophic tyrosine Kinase, Receptor, Type 3 (NTRK3) (aa 32-429) |
Clone | 7H6 |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1 |
Format | ascites |
Size | 100 µL |
Concentration | n/a |
Applications | ELISA,Western Blotting (WB),Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | NTRK3 (neurotrophic tyrosine kinase, receptor, type 3), it is a member of the neurotrophic tyrosine receptor kinase (NTRK) family and plays an important role in the development and maintenance of neural tissues. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. Signalling through this kinase leads to cell differentiation and may play a role in the development of proprioceptive neurons that sense body position. Mutations in this gene have been associated with medulloblastomas, secretory breast carcinomas and other cancers. |
Immunogen | Purified recombinant extracellular fragment of human NTRK3 (AA 32-429) fused with hIgGFc tag expressed in HEK293 cells. |
Other Names | TRKC|gp145(trkC)|AW125844|Ntrk3_tv3|TrkC|trkC |
Gene, Accession # | Gene ID: 4916 |
Catalog # | ABIN969323 |
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Order / More Info | Neurotrophic tyrosine Kinase, Receptor, Type 3 (NTRK3) (aa 32-429) Antibody from ANTIBODIES-ONLINE GmbH |
Product Specific References | PubMed: 12210087 |
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