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| Product Name | N-3-oxo-tetradec-7(Z)-enoyl-L-Homoserine lactone |
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| Description | Purity >98%. Quorum sensing is a regulatory system used by bacteria for controlling gene expression in response to increasing cell density. This regulatory process manifests itself with a variety of phenotypes including biofilm formation and virulence factor production. Coordinated gene expression is achieved by the production, release, and detection of small diffusible signal molecules called autoinducers. The N-acylated homoserine lactones (AHLs) comprise one such class of autoinducers, each of which generally consists of a fatty acid coupled with homoserine lactone (HSL). Regulation of bacterial quorum sensing signaling systems to inhibit pathogenesis represents a new approach to antimicrobial therapy in the treatment of infectious diseases. AHLs vary in acyl group length (C4 -C18 ), in the substitution of C3 (hydrogen, hydroxyl, or oxo group), and in the presence or absence of one or more carbon-carbon double bonds in the fatty acid chain. These differences confer signal specificity through the affinity of transcriptional regulators of the LuxR family. 3-oxo-C14 :1-Delta7 cis-(L)-HSL is a bacterial quorum sensing compound that possesses antimicrobial activity, the ability to inhibit biofilm formation, and exhibits immune suppressive activity. This compound is structurally related to other 3-oxo-monounsaturated (N-acylated homoserine lactones) AHLs such as 3-oxo-C16 :1-Delta11 cis-(L)-HSL (). |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 3-oxo-N-[(3S)-tetrahydro-2-oxo-3-furanyl]-7-tetradecenamide, 3-oxo-C14:1-Delta7cis-(L)-HSL |
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| Gene, Accession, CAS # | CAS: 482598-46-9 |
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| Catalog # | LS-H8876 |
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| Order / More Info | N-3-oxo-tetradec-7(Z)-enoyl-L-Homoserine lactone from LIFESPAN BIOSCIENCES INC. |
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| Product Specific References | n/a |
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