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| Product Name | UBLE1A (SAE1) Recombinant protein |
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| Description | MW: ~65 kDa. Recombinant full-length human UBLE1A (SAE1) was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag.Scientific Background: UBLE1A (also known as SAE1) or SUMO1 activating enzyme subunit 1 is involved in regulating protein structure and intracellular localization. SAE1 and UBA2 form a heterodimer that functions as a SUMO-activating enzyme for the sumoylation of proteins (1). The SAE1/SAE2 dimer functions in SUMO1 activation in a manner analogous to |
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| Size | 0.02 mg, 0.05 mg |
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| Concentration | n/a |
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| Applications | Western Blot (WB) |
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| Other Names | [SAE1; SUA1; HSPC140; AOS1; FLJ3091; HSPC140; UBLE1A(SAE1) protein] |
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| Gene, Accession, CAS # | UBLE1A (SAE1), Gene ID: 10055, Accession: NP_005491.1 |
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| Catalog # | MBS515376 |
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| Order / More Info | UBLE1A (SAE1) Recombinant protein from MYBIOSOURCE INC. |
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| Product Specific References | 1. Okuma, T. et.al: In vitro SUMO-1 modification requires two enzymatic steps, E1 and E2. Biochem. Biophys. Res. Commun. 254: 693-698, 1999. 2. Kessler, J. D. et.al: A SUMOylation-dependent transcriptional subprogram is required for Myc-driven tumorigenesis. Science 335: 348-353, 2012. |
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