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| Product Name | THOC7, Recombinant, Human, aa1-204, His-Tag |
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| Description | Purity ~90% (SDS-PAGE). THOC7 is required for efficient export of polyadenylated RNA. This protein acts as component of the THO subcomplex of the TREX complex which is thought to couple mRNA transcription, processing and nuclear export, and which specifically associates with spliced mRNA and not with unspliced pre-mRNA. TREX is recruited to spliced mRNAs by a transcription-independent mechanism, binds to mRNA upstream of the exon-junction complex (EJC) and is recruited in a splicing- and cap-dependent manner to a region near the 5' end of the mRNA where it functions in mRNA export to the cytoplasm via the TAP/NFX1 pathway. The TREX complex is essential for the export of Kaposi's sarcoma-associated herpesvirus (KSHV) intronless mRNAs and infectious virus production. Source: Recombinant protein corresponding to aa1-204 from human THOC7, fused to His-tag at N-terminus, expressed in E.coli. Molecular Weight: ~26.1kD (227aa), confirmed by MALDI-TOF Applications: Suitable for use in SDS-PAGE |
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| Size | 50ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | THOC7, Recombinant, Human, aa1-204, His-Tag (THO Complex Subunit 7 Homolog, Ngg1-Interacting Factor 3-Like Protein 1-Binding Protein 1, NIF3L1BP1) |
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| Gene, Accession, CAS # | Accession: NP_079351 |
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| Catalog # | 218629 |
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| Order / More Info | THOC7, Recombinant, Human, aa1-204, His-Tag from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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