| 产品详情 |
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| Product Name | GDC-0941 |
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| Description | Purity >98%. The phosphatidylinositol 3-kinase (PI3K) signaling pathway has central roles in cell growth, development, and survival. GDC-0941 is a potent pan inhibitor of class I catalytic subunits of PI3K, inhibiting p110Alpha, Beta, Delta, and Gamma with IC50 values of 3, 33, 3, and 75 nM, respectively. It is much less effective against class II-IV isoforms of PI3K and against mTOR. GDC-0941 inhibits the growth of certain types of cancer cells and blocks signaling through PI3K to Akt, both in cells and in vivo . |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 2-(1H-indazol-4-yl)-6-[[4-(methylsulfonyl)-1-piperazinyl]methyl]-4-(4-morpholinyl)-thieno[3,2-d]pyrimidine, GNE-0941, Pictilisib, Pictrelisib |
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| Gene, Accession, CAS # | CAS: 957054-30-7 |
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| Catalog # | LS-H7914 |
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| Order / More Info | GDC-0941 from LIFESPAN BIOSCIENCES INC. |
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| Product Specific References | n/a |
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| 产品资料 |
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