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| Product Name | MAP Kinase 2, Recombinant, Mouse, Unactive |
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| Description | Purity ≥99.5% as determined by SDS-PAGE and Coomassie blue staining. Purified by glutathione-sepharose chromatography. An important convergence point involved in the signal transduction pathways of many different growth factors, hormones, and cytokines is a family of 41-44kD serine/threonine kinases collectively called either MAPKs (for mitogen-activated protein kinases) or Erks (for extracellular-regulated kinases). MAPK is activated by sequential phosphorylation on both tyrosine and threonine residues by the dual tyrosine/threonine kinase MEK (MAPK kinase). The serine/threonine kinase Raf can phosphorylate and activate MEK, in turn, during intracellular signaling. Activation of MAPK is directly regulated by a specific MAPK phosphatase and indirectly regulated by protein kinase A activation which results in inhibition of Raf activity in mammalian cells. Source Unactive, recombinant full-length mouse p42 MAP Kinase 2/Erk2 fused to GST-Tag at N-terminus, expressed in E.coli. Specific Ac |
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| Size | 50ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | MAP Kinase 2, Recombinant, Mouse, Unactive (Mitogen-activated Protein Kinase 2, MAPK 2, MAPK2, Extracellular Signal-regulated Kinase 2, ERK2, ERK-2, ERK, ERT1, MAP Kinase Isoform p42, Mitogen-activated Protein Kinase 1, MAP Kinase 1, MAPK 1, Mapk1, Mapk, p42mapk, p42-MAPK, Prkm1, PRKM2) |
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| Gene, Accession, CAS # | Accession: NM_011949.3, SwissProt: P63085 |
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| Catalog # | M2362-07 |
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| Order / More Info | MAP Kinase 2, Recombinant, Mouse, Unactive from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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