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| Product Name | Recombinant Human Estrogen receptor beta |
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| Description | 2-323. MW: 51.79kD. Purity >90% as determined by SDS-PAGE. Nuclear hormone receptor. Binds estrogens with an affinity similar to that of ESR1, and activates expression of reporter genes containing estrogen response elements (ERE) in an estrogen-dependent manner (PubMed:20074560). Isoform beta-cx lacks ligand binding ability and has no or only very low ere binding activity resulting in the loss of ligand-dependent transactivation ability. DNA-binding by ESR1 and ESR2 is rapidly lost at 37 degrees |
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| Size | 0.01 mg (E-Coli), 0.05 mg (E-Coli), 0.2 mg (E-Coli), 0.5 mg (E-Coli), 1 mg (E-Coli) |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | [ER-beta; Nuclear receptor subfamily 3 group A member 2] |
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| Gene, Accession, CAS # | ESR2, Gene ID: 2100, Accession: NP_001035365.1 |
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| Catalog # | MBS969514 |
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| Order / More Info | Recombinant Human Estrogen receptor beta from MYBIOSOURCE INC. |
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| Product Specific References | Repression of estrogen receptor beta function by putative tumor suppressor DBC1.Koyama S., Wada-Hiraike O., Nakagawa S., Tanikawa M., Hiraike H., Miyamoto Y., Sone K., Oda K., Fukuhara H., Nakagawa K., Kato S., Yano T., Taketani Y.Biochem. Biophys. Res. Commun. 392:357-362(2010) |
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