| 产品详情 |
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| Product Name | RAGE BioAssay™ ELISA Kit, Rat |
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| Description | RAGE, the Receptor for Advanced Glycation Endproducts, is a 35kD transmembrane receptor of the immunoglobulin super family. It is also known as ``AGER''. AGER gene is mapped to chromosome 6p21.3 by mapping by contiguous cosmids and YAC clones and by fluorescence in situ hybridization. The expression of RAGE is particularly increased in neurons close to deposits of amyloid beta peptide and to neurofibrillary tangles. RAGE has been linked to several chronic diseases, which are thought to result from vascular damage. The pathogenesis is hypothesized to include ligand binding upon which RAGE signals activation of the nuclear factor kappa B (NF-κB). Intended Use: RAGE BioAssay™ ELISA Kit is a sandwich ELISA for quantitative detection of rat RAGE in cell culture supernates, serum and plasma (heparin, EDTA). Range: 78-5000pg/ml Sensitivity: <10pg/ml Specificity: Natural and recombinant rat RAGE Crossreactivity: No detectable crossreactivity with other relevant proteins Kit Component |
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| Size | 96 tests |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | Gene ID: 81722, SwissProt: Q63495 |
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| Catalog # | 144021 |
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| Order / More Info | RAGE BioAssay™ ELISA Kit, Rat from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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