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| Product Name | RAGE, Recombinant, Human, His-Tag |
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| Description | Purity ~95% (SDS-PAGE, HPLC). Advanced glycosylation end product-specific receptor, also known as receptor for advanced glycosylation end products, AGER and RAGE, belongs to the immunoglobulin superfamily of cell surface molecules. It lies within the major histocompatibility complex (MHC) class III region on chromosome 6. Besides AGEs, AGER is also able to bind other ligands which is thought to result in pro-inflammatory gene activation. It is known that AGER serves as a mediator of both acute and chronic vascular inflammation in certain conditions such as atherosclerosis and in particular as a complication of diabetes. Furthermore, it plays an important role in regulating the production/expression of TNF-alpha, oxidative stress, and endothelial dysfunction in type 2 diabetes. Source: Recombinant protein corresponding to aa23-344 from human RAGE fused with a poly-histidine tag at the C-terminus, expressed in human cells. Molecular Weight: ~35kD Endotoxin: <0.1ng/ug |
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| Size | 10ug, 50ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | RAGE, Recombinant, Human, His-Tag (Receptor for Advanced Glycosylation End Products, Advanced Glycosylation End Product-specific Receptor, AGER) |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | 169732 |
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| Order / More Info | RAGE, Recombinant, Human, His-Tag from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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