| 产品详情 |
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| Product Name | PF-4800567 |
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| Description | Purity >98%. PF-4800567 is a selective inhibitor of casein kinase 1e (CK1e; IC50 = 32 nM) with greater than 20-fold selectivity over CK1Delta. It blocks CK1e-mediated PER3 nuclear localization and PER2 degradation, both of which are proteins important for maintaining circadian rhythms in cells. PF-4800567 has been used in the study of the CK1 enzymes in the regulation of circadian rhythm and is also reported to have neuroprotective effects. |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 3-[(3-chlorophenoxy)methyl]-1-(tetrahydro-2H-pyran-4-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine |
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| Gene, Accession, CAS # | CAS: 1188296-52-7 |
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| Catalog # | LS-H9347 |
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| Order / More Info | PF-4800567 from LIFESPAN BIOSCIENCES INC. |
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| Product Specific References | n/a |
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| 产品资料 |
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